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Table 2 Participant, diagnosis, intervention, comparators, duration, outcome measures, results

From: Effect of respiratory therapy on pulmonary functions in children with cerebral palsy: a systematic review

Study

Participant

Diagnosis

Intervention

Comparators

Duration

Outcome measures

Results

1-Rothman [19]

N = 10 (Exp. gp = 5, Cont.gp = 5)

Age (years) 5–9

Spastic diaplegic CP children

Breathing exercises 5–7 min/day

Bobath treatment approach

8 weeks

VC

FEV1

-Significant improvement of VC mean = 0.46 L at p = 0.005

-Both groups showed no significant difference in the pretest and posttest values

2-Hutzler et al. [20]

N = 46 (Exp.gp = 23, cont.gp = 23)

Age (years) 5–7

Spastic diaplegic, hemiplegia, quadriplegia, and ataxic CP children

Swimming session twice weekly + group physical activity once weekly (30 min duration)

Bobath physical therapy (4 day/week; 30 min duration)

6 months

VC

WOS

-Significant increase in mean value of VC = 35.8 at p = 0.009.

-Significant increase in raw scores of WOS with mean value = 33.4 at p < 0.001

3-Lee et al. [21]

N = 22 (Exp.gp = 11, cont.gp = 11)

Age (years) 6–12

Spastic diaplegic, hemiplegic CP children

Feedback respiratory training (15 min) + conventional rehabilitation (30 min) with 10 min break in between 3 days/week

CPT (gross motor activities) 20 min, 3 days/ week

4 weeks

Pulmonary functions (FVC, FEV1, PEF, VC, ERV, TV, IRV)

The experimental group showed significant increase in VC and FEV1 mean values (1.5, 1.4) respectively at p < 0.005 with no significant changes in other measures.

4-Choi et al. [22]

N = 50 (Exp.gp = 25, cont.gp = 25)

age (years) 8–15

Spastic diaplegic, hemiplegic, quadriplegic, and triplegic CP children

ISE 10–15 breath/session 10 sessions daily + conventional rehabilitation + occupational therapy

CPT + occupational therapy 5 times/week

4 weeks

-Pulmonary functions (FEV1, FVC, PEF, FEV1/FVC).

-GMF

-MPT

-The experimental group showed significant increase in FEV1 and FVC mean values (1.57, 2.15) respectively at p < 0.005.

-Both groups showed no significant difference in the pretest and posttest values in GMF.

-Significant increase in MPT mean value—12.13 at p = 0.001

5-Shin and Kim et al. [23]

N = 15 (Exp.gp = 8, Cont.gp = 7)

Age (mean): Exp 9.25, Con.gp 9.57

Spastic CP children

Upper extremity resistance exercise using thera band (20–30 min/session) + NDT (30 min 2 session/week)

NDT (30 min 2 session/week)

8 weeks

-Pulmonary functions (FVC, FEV1, PEF)

-Respiratory muscle strength (MIP, MEP)

-Grip strength

-Significant improvement in FVC, FEV1, PEF, and MIP with mean values 0.09, 0.17, 0.46, and 1.88, respectively group with no statistical difference between both groups

-Grip strength and MEP significantly improved in Exp.gp with mean value (0.82, 6) respectively at p < 0.005

6-Keles et al. [24]

N = 28 (Exp.gp = 14, Cont.gp = 14)

Age (years) 7–14

Spastic diaplegic, hemiplegic CP children

Inspiratory muscle training at 30% MIP (twice daily; 15 min) + CPT (40 min/day, 3 days/week) + home program of breathing exercises

Inspiratory muscle training at 5% MIP (15 min twice daily) + CPT (40 min/day, 3 days/week) + home program of breathing exercises

6 weeks

-Pulmonary functions (FEV1, FVC, FEF, PEF, MIP, MIP%, MEP, MIP%)

-Trunk control

-Daily living activities

-Functional exercise capacity

-Quality of life

-No significant difference in pulmonary functions between both groups p > 0.005.

-Significant improvements in MIP mean value = 28.66 at p < 0.001

-Significant improvement in trunk control of study group mean value = 4.50 (p < 0.001)

-Significant improvement in self-care (2.28, p = 0.007), mobility (3.39, p = 0.001), and social function (2.56) domains in study group only and no significant difference bet. 2 groups in other domains in PEDI-CAS subscale scores

-Significant improvement in distance covered during 6MWT in study group only (66.38, p < 0.001)

-Significant improvement in social well-being and acceptance (10.44, p < 0.001) and functioning domain (3.59, p = 0.004) scores in study group only, no significant difference bet. groups in other domains of CPQOL-Child

7-Kwon and Kim [25]

N = 34 (Exp.gp = 17, Cont.gp = 17)

Age (years) 4–12

Spastic CP children

Task-specific movement patterns with loaded resistance (40 min twice/week) + ROM and stretching exercise (5–10 min)

Task-specific movement patterns without loaded resistance (40 min twice/week) + ROM and stretching exercise (5–10 min)

12 weeks

-Respiratory functions (FVC, FEV1, PEF)

-Thickness of abdominal muscles

-Significant improvement in mean values of FVC (1.72), FEV1 (1.69), PEF(1.69) at p < 0.05 in Exp. group

-Significant improvement in abdominal muscle thickness (p < 0.05) in Exp. group

8-Kanna and Balabaskar [26]

N = 30 (Exp.gp = 15, Cont.gp = 15)

Age (years) 6–14

Spastic quadriplegic CP children

Respiratory exercises along with NDT for 45 min (30 min and 15 min), 5 days in a week

NDT for 45 min, 5 days in a week

6 weeks

Pulmonary functions (FVC, FEV1, FEV1/FVC ratio PEF)

Significant improvement in mean values of FVC (1.65 + 0.98), FEV1 (1.28 + 0.84), PEF (2.32 + 1.23), and FEV1/FVC (80.63 + 16.80) in experimental group (p < 0.05)

  1. 6MWT 6-minute walk test, Cont.gp Control group, CP Cerebral palsy, CPQOL Cerebral palsy quality of life, CPT Conventional physical therapy, ERV Expiratory reserve volume, Exp.gp Experimental group, FEF Forced expiratory flow, FEV1 Forced expiratory volume at 1 s, FVC Forced vital capacity, GMFM Gross motor function measure, IRV Inspiratory reserve volume, ISE Incentive spirometry exercise, MEP Maximal expiratory pressure, MIP Maximal inspiratory pressure, N Total number, NDT Neurodevelopmental treatment, PEDI-CAS Pediatric evaluation of disability inventory-caregiver assistance scale, PEF Peak expiratory flow, ROM Range of motion, TV Tidal volume, VC Vital capacity