Mean difference | P value | 95% confidence interval for difference | |||
---|---|---|---|---|---|
Lower bound | Upper bound | ||||
Physical functioning | |||||
Baseline | Post-4 weeks | − 10.726* | 0.003 | − 17.519 | − 3.933 |
Post-8 weeks | − 29.597* | 0.000 | − 35.610 | − 23.583 | |
Post-12 weeks | − 44.677* | 0.000 | − 50.689 | − 38.665 | |
Post-4 weeks | Post-8 weeks | − 18.871* | 0.000 | − 24.680 | − 13.062 |
Post-12 weeks | − 33.952* | 0.000 | − 40.656 | − 27.247 | |
Post-8 weeks | Post-12 weeks | − 15.081* | 0.000 | − 20.756 | − 9.406 |
Limitation to physical health | |||||
Baseline | Post-4 weeks | − 23.387* | 0.002 | − 37.382 | − 9.392 |
Post-8 weeks | − 49.194* | 0.000 | − 64.985 | − 33.402 | |
Post-12 weeks | − 62.903* | 0.000 | − 78.040 | − 47.766 | |
Post-4 weeks | Post-8 weeks | − 25.806* | 0.000 | − 39.301 | − 12.312 |
Post-12 weeks | − 39.516* | 0.000 | − 55.001 | − 24.031 | |
Post-8 weeks | Post-12 weeks | − 13.710* | 0.009 | − 23.710 | − 3.709 |
Limitation to emotional problems | |||||
Baseline | Post-4 weeks | − 21.538* | 0.001 | − 33.163 | − 9.913 |
Post-8 weeks | − 41.936* | 0.000 | − 57.392 | − 26.481 | |
Post-12 weeks | − 45.162* | 0.000 | − 62.894 | − 27.430 | |
Post-4 weeks | Post-8 weeks | − 20.398* | 0.001 | − 31.647 | − 9.149 |
Post-12 weeks | − 23.624* | 0.002 | − 38.165 | − 9.083 | |
Post-8 weeks | Post-12 weeks | − 3.225 | 0.540 | − 13.864 | 7.413 |
Energy and fatigue | |||||
Baseline | Post-4 weeks | − 7.500* | 0.039 | − 14.607 | − 0.393 |
Post-8 weeks | − 22.097* | 0.001 | − 33.952 | − 10.241 | |
Post-12 weeks | − 39.032* | 0.000 | − 49.357 | − 28.707 | |
Post-4 weeks | Post-8 weeks | − 14.597* | 0.001 | − 22.612 | − 6.581 |
Post-12 weeks | − 31.532* | 0.000 | − 39.647 | − 23.417 | |
Post-8 weeks | Post-12 weeks | − 16.935* | 0.000 | − 22.411 | − 11.460 |
Emotional wellbeing | |||||
Baseline | Post-4 weeks | − 3.935 | 0.315 | − 11.801 | 3.930 |
Post-8 weeks | − 13.677* | 0.001 | − 21.631 | − 5.724 | |
Post-12 weeks | − 23.742* | 0.000 | − 30.486 | − 16.998 | |
Post-4 weeks | Post-8 weeks | − 9.742* | 0.014 | − 17.330 | − 2.154 |
Post-12 weeks | − 19.806* | 0.000 | − 27.216 | − 12.397 | |
Post-8 weeks | Post-12 weeks | − 10.065* | 0.001 | − 15.821 | − 4.308 |
Social functioning | |||||
Baseline | Post-4 weeks | − 14.274* | 0.000 | − 21.561 | − 6.987 |
Post-8 weeks | − 24.919* | 0.000 | − 32.223 | − 17.616 | |
Post-12 weeks | − 36.210* | 0.000 | − 44.182 | − 28.237 | |
Post-4 weeks | Post-8 weeks | − 10.645* | 0.000 | − 15.509 | -5.781 |
Post-12 weeks | − 21.935* | 0.000 | − 27.896 | − 15.975 | |
Post-8 weeks | Post-12 weeks | − 11.290* | 0.000 | − 16.504 | − 6.077 |
Pain | |||||
Baseline | Post-4 weeks | − 6.774 | 0.072 | − 14.191 | 0.642 |
Post-8 weeks | − 25.323* | 0.000 | − 36.053 | − 14.593 | |
Post-12 weeks | − 40.323* | 0.000 | − 48.605 | − 32.040 | |
Post-4 weeks | Post-8 weeks | − 18.548* | 0.000 | − 27.660 | − 9.437 |
Post-12 weeks | − 33.548* | 0.000 | − 41.336 | − 25.761 | |
Post-8 weeks | Post-12 weeks | − 15.000* | 0.000 | − 21.119 | − 8.881 |
General health | |||||
Baseline | Post-4 weeks | − 1.258 | 0.631 | − 6.559 | 4.043 |
Post-8 weeks | − 6.581* | 0.044 | − 12.963 | − 0.198 | |
Post-12 weeks | − 10.645* | 0.001 | − 16.381 | − 4.909 | |
Post-4 weeks | Post-8 weeks | − 5.323* | 0.016 | − 9.575 | − 1.070 |
Post-12 weeks | − 9.387* | 0.000 | − 13.719 | − 5.056 | |
Post-8 weeks | Post-12 weeks | − 4.065 | 0.145 | − 9.613 | 1.484 |