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Bulletin of Faculty of Physical Therapy
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Systematic review: exercise training for equinus deformity in children with cerebral palsy

Bulletin of Faculty of Physical Therapy volume 27, Article number: 37 (2022) Cite this article

Abstract

Background

Children with spastic cerebral palsy have motor deficits that can lead to joint contractures. Ankle equinus deformity is the most common foot deformity among children with CP. It is caused by spasticity and muscular imbalance in the gastrocnemius-soleus complex. Exercise enhances ankle function, improves gait in children with CP, and prevents permanent impairment. Therefore, there is a need to investigate the effectiveness of different types of exercise used in equine management. The aim of this review is to assess the evidence of the effectiveness of exercise training on equinus deformity in children with cerebral palsy.

Methodology

The American Academy for Cerebral Palsy and Developmental Medicine and Preferred Reporting Items for Systematic Reviews and Meta-Analyses methodology were used to conduct this systematic review. Four databases (PubMed, Cochrane Library, Physiotherapy Evidence Database (PEDro), and Google Scholar) were searched till January 2022 using predefined terms by two independent reviewers. Randomized controlled trials published in English were included. This review included seven studies with 203 participants ranging in age from 5 to 18 years. Methodological quality was assessed using AACPDM, PEDro scale; also, levels of evidence adopted from modified Sacket’s scale were used for each study. Primary outcomes were dorsiflexion angle, plantar flexion angle, and plantar flexors strength.

Results

The quality of studies ranged from good (six studies) to fair (one study). The level of evidence was level 1 (six studies) and level 2 (one study) on modified Sacket’s scale. There is a low risk of bias in the included studies. Meta-analysis revealed a non-significant difference in plantar flexor strength, plantar flexion angle, and dorsiflexion angle between the study and control group.

Conclusions

There is a need for high-quality studies to draw a clear conclusion as the current level of evidence supporting the effectiveness of various types of exercises on equinus deformity in children with cerebral palsy is still weak.

Background

Systematic reviews use a structured and pre-defined procedure that requires the use of methodological approaches (comprehensive methods) to ensure that the results are both reliable and purposeful to the patients [1]. These reviews are widely used to inform the development of consistently reliable clinical guidelines [2,3,4], and they may be considered the best evidence-based healthcare [1]. A systematic review, according to the Cochrane handbook, uses explicit, systematic methods to minimize bias, thus providing more trustworthy findings from which conclusions can be reached and decisions can be made [5].

Cerebral palsy (CP) is defined as “a group of developmental disorders of movement and posture that cause functional limitation or disability associated with disturbances occurring in the foetal or infant brain”. The motor impairment may include a seizure disorder and also affection of sensation, cognition, communication, and/or behaviour, in addition to secondary musculoskeletal disorders that may also exist [6]. It is commonly caused by a brain injury that occurs prior to or during birth, which is the major contributing factor. It can also happen between the ages of 3 and 5 years [7]. Cerebral palsy is a complex disease resulting from injury to the developing brain rather than a single illness [8]. The severity as well as the patterns of motor involvement and associated impairments such as those of communication, intellectual ability, and epilepsy varies greatly [7]. The mixture of postural and gait abnormalities is one of the most noticeable characteristics found in children with CP [9, 10]. Paresis and spasticity, which are caused by a lesion in the upper motor neuron, are significant contributors to the motor impairments and can lead to the development of joint contractures, which are dynamic at first but can become fixed joint deformities if left untreated. Equinus is often associated with spasticity in the gastrosoleus muscle complex (GSC) [11].

Ankle equinus deformity, which is the inability to dorsiflex the foot beyond the plantigrade level, or neutral [12, 13], is the most common foot deformity among children with CP [14, 15]. Patients with equinus have a lack of ankle dorsiflexion and toe-walking pattern, which causes ankle instability, the risk of falling, dysfunction, and consequent joint deformity [16,17,18]. Spasticity and muscle imbalance, with a strong dominance of the gastrocnemius-soleus complex, cause equinus deformity. Experimental evidence suggests that spastic muscles grow at a slower rate than muscles and bones in their normal state, supporting the development of contracture [19]. Since this deformity is initially dynamic, stretching and orthosis may be effective treatments.

Exercise and muscle tone management are both significant treatment strategies for improving ankle function [20]. Strength training is an effective method to reduce muscle weakness, which is the most common consequence of CP, while also improving functional ability [21, 22]. Strengthening programmes targeting lower extremities play a critical role in improving the functional abilities such as walking [21, 23, 24] and the Gross motor function classification system (GMFCS) scoring after strength training completion [21]. Stretching, on the other hand, improves the extensibility of the muscle and helps to avoid or postpone the need for orthopaedic interventions. Furthermore, stretching is important in preventing permanent muscle or joint shortening (muscle contractures, for example) as well as reducing joint stiffness and decreasing functional movement [25].

Therapeutic interventions such as stretching and active movement training goal are enhancing ankle function and improving gait in children with CP [26]. The aim of this study is to conduct a systematic review of the quality of evidence regarding the efficacy of several types of exercises used in the management of equine deformity in children with cerebral palsy.

Main text

Methods

Two reviewers conducted an electronic search up to January 2022. To find relevant published studies, the following databases were searched: the Cochrane Library, the Physiotherapy Evidence Database (PEDro), PubMed, and Google Scholar. The following keywords were used to search those databases: “Cerebral palsy”, “equinus gait”, “ gastrocnemius tightness”, “dorsiflexor weakness”, “equinus deformity”, “equinus contracture”, “Talipes Equinus”, “exercise therapy”, “Resistance Training”, “ Physical Activity”, “exercise fitness”, “Exercise Movement Technique”. The Cochrane Handbook for Systematic Reviews of Interventions [5], the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) methodology for developing systematic reviews of treatment interventions [27], and the Preferred Reporting Items for Systematic Reviews (PRISMA) guidelines [28] were used to conduct this systematic review. All potentially eligible articles were obtained in full text, and reference lists from eligible studies were also screened.

Eligibility criteria

The following criteria were used to determine whether studies were eligible:

  • Study design: randomized controlled trials (RCT)

  • Participants: children with various forms of CP from both sexes; their age is up to 18 years old

  • Intervention: exercise training (strengthening exercises, stretching exercises, or a combination of strengthening and stretching exercises)

  • Outcomes: dorsiflexion angle, plantar flexion angle, plantar flexors strength

  • Language: available English full-text studies

Criteria for exclusion

  • Studies that have not yet been published

  • Non-RCT study designs, such as narrative reviews, case reports or series, observational studies, and conference proceedings

  • Research that investigated outcomes that were unrelated to our scope

  • Studies that combined exercise training with other modalities

Data extraction

Two reviewers filled the data extraction sheet developed by the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) [27] to extract relevant information or data, such as the following: (a) the author and year of publication; (b) population information, including the number of children by diagnosis and age; (c) study design; (d) methodology; (e) measured outcomes; and (f) results. When compared to a similar tool, the inter-rater reliability and convergent validity of the AACPDM’s evidence and study quality ratings for group design studies are acceptable [28].

Methodological quality assessment

The current systematic review’s methodological quality was assessed using the AACPDM rating system of quality assessment [27] and the PEDro scale. PEDro is a reliable valid indicator of clinical trial methodological quality [29]. The internal validity of the included studies was assessed through PEDro scale criteria of adequate randomization; allocation concealment; blinding of participants, therapists, and assessor; incomplete outcome data; similar baseline; and use of intention-to-treat analysis. The items are scored as either present (1) or absent (0). To reach the final decision, the methodological quality of the included studies was independently assessed by two reviewers, and discrepancies were resolved by consulting with a third reviewer. After categorizing each item as “present” or “absent”, the total score of each study was calculated as the sum of “present” responses. Scores range from 0 to 10, with higher scores indicating higher RCT methodological quality. The individual study’s quality would be rated as excellent (score 9–10), good (score 6–8), fair (score 4–5), or poor (score 3) [30].

The AACPDM questions include clear eligibility criteria, reliable measures of outcome, blinding of assessors, power calculations, and controlling for other sources of bias (for example, unclear type of random sequence generation or allocation concealment, insufficient follow-up, lack of intention to treat). Each question should be answered with “yes” (criterion/criteria present) or “no” (criterion/criteria absent). Individual studies’ quality would be assessed as strong (“yes” on 6–7 of the questions), moderate (scoring 4 or 5), or weak (score 3) for group studies [27].

Level of evidence

The modified Sackett scale [31] was used to assess the level of evidence in all included studies. The modified Sackett scale has five levels of evidence, which are as follows: level 1 if the study is RCT (PEDro score ≥ 6); level 2 if the study is RCT (PEDro score < 6), prospective controlled trial or cohort; level 3 if the study is case-control; level 4 if the study is one-group pretest-posttest or case series; and level 5 if the study is a case report. The strength of the evidence for the intervention was determined using this 5-level scale.

Assessment of risk of bias of included studies

Bias is defined as a systematic error in results or inferences. Biases can work in both ways: different biases can lead to an underestimation or overestimation of the true intervention effect. Biases can range in intensity. It is usually impossible to determine the extent to which biases influenced the findings of a particular study. The domains that represent the risk of bias in the current systematic review are random sequence generation, allocation concealment, selective reporting, other sources of bias, blinding (participants and personnel and outcome assessment), and incomplete outcome data [32].

Data analysis

If two or more published studies were similar in terms of intervention, patient demographics, outcome measures, and adequate quality, data were statistically summarized. Data from homogenous studies were analysed using Review Manager (RevMan – version 5.4.1, The Nordic Cochrane Center, The Cochrane Collaboration, Copenhagen, Denmark, 2021). A formal meta-analysis was conducted for all outcomes if the data were sufficient. Pooled data were expressed as the mean difference (MD) with 95% CI. Meta-analyses including studies with different scales were summarized using the standardized mean difference (SMD) with the 95% CI. For the studies reporting the mean and 95% CI, the SD of the paired difference was calculated in 2 steps: (1) dividing the confidence interval (CI) by the t constant according to the degree of freedom that depends on the sample size to get the standard error of the mean (SEM), then (2) applying the equation SD = SE × SQRT (n) to calculate the SD. The heterogeneity test (I2) helps to assess whether there are differences between the studies included in the meta-analysis [33,34,35]. If the I2 value is ˂ 50%, and the test P value is ˃ 0.05, so the studies can be considered homogenous. Between-study statistical heterogeneity was explored and quantified using the I2 test. By default, the fixed-effect model was used in all analyses. The 2-sided statistical analysis testing was considered the α-error level at 0.05.

Results

Literature search

The search strategy revealed 5170 articles from the previously mentioned databases as follows: Cochrane Library (13), PEDro (1), PubMed (16), and Google Scholar (5140). There were duplicate articles (9). The remaining 5161 articles, titles, and abstracts were independently screened by the reviewers. Thirteen articles were filtered based on full text; as shown in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses flow chart (PRISMA) (Fig. 1) [36], 5148 articles were excluded because they were outside the scope, used different therapies, the children’s diagnosis was not CP, or the outcome of interest was absent. The remaining seven studies made the basis for the current systematic review.

Fig. 1
figure 1

PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flowchart

Full size image

This systematic review includes meta-analysis for five studies and descriptive analysis for two studies because of the difference in terms of intervention.

Study characteristics

In terms of general participant characteristics, outcome measures, and evaluation procedures, there was some homogeneity among the studies included (Table 1). As a result, these studies underwent meta-analysis.

Table 1 Participant, diagnosis, intervention, duration, outcome measures, and results
Full size table

Participant characteristics

Two hundred and three children ranged from 5 to 18 years of age were diagnosed with spastic cerebral palsy with [GMFCS] levels I–III [37, 38, 40,41,42] and [GMFCS] levels I and II [39, 42, 43]. One study specifies CP type which is diplegic [42].

Intervention

All studies investigated the effect of different types of exercise training on equine deformity in children with cerebral palsy (strengthening exercise [37, 39, 41,42,43], stretching exercise [39, 40], combined strengthening and stretching exercise [38]).

Types of outcomes measured

Dorsiflexion angle [39, 43], plantar flexion angle [41, 43], and plantar flexors strength [37, 41,42,43].

Measurements of the outcomes

All studies used a dynamometer for measuring plantar flexors strength, goniometry, and markers for measuring plantar flexion angle and dorsiflexion angle.

Methodological quality level

Table 2 shows how each study scored on the PEDro scale. The mean score of the 7 studies was 6.9. Three studies were rated an 8 [37, 40, 42], one was rated a 7 [41], two studies were given a 6 [38, 39], and one research was given a 5 [43] that represents “fair” quality.

Table 2 PEDro score
Full size table

The score of each study on the AACPDM conduct questions is also presented in Table 3. The mean score of the 7 studies was 6.3. Three studies had a score of 7 [37, 41, 42], and three studies received a score of 6 [38,39,40] which represents “strong” quality. A score of 5 was assigned to one study [43], indicating “moderate” quality.

Table 3 AACPDM methodological quality
Full size table

The AACPDM conduct questions: (a) Had inclusion and exclusion criteria of the study participants well defined and followed? (b) Had the intervention well described and was there adherence to the intervention protocol? (For 2 group designs, had the control intervention also well described?) Both parts of the question must be met to score “yes.” (c) Had the measures used clearly described, valid, and reliable for measuring the outcomes of interest? (d) Had the outcome assessor unaware of the intervention status of the participants (i.e. were the assessors masked)? (e) Did the researchers conduct and describe appropriate statistical measures including power calculations? Both parts of the question must be met to score “yes.” (f) Had dropout/loss to follow-up reported and less than 20%? For 2 group designs, was dropout balanced? (g) Considering the potential within the study design, had the authors use appropriate methods for controlling confounding variables and limiting potential biases?

Level of evidence

According to the modified Sacket scale [31], five studies were ranked level 1 and two studies ranked level 2.

Descriptive synthesis of the risk of bias

All studies had random allocation of participants, had groups of similar baselines, reported results of between-group statistical comparisons, provided measures of variability for at least one outcome, and specified the eligibility criteria. There were five studies with concealed allocation [37, 38, 40,41,42], six studies with blinded assessors [37,38,39,40,41,42], and only one study with blinded participants and blinded therapists [42].

Meta-analysis

A meta-analysis was performed for three variables: dorsiflexion angle in the immediate assessment (Fig. 2), plantar flexion angle in the immediate assessment (Fig. 3) and the follow-up assessment (Fig. 4), and plantar flexion strength in the immediate assessment (Fig. 5) and the follow-up assessment (Fig. 6).

Fig. 2
figure 2

Forest plot of comparison between study and control groups regarding dorsiflexion angle — post-intervention

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Fig. 3
figure 3

Forest plot of comparison between study and control groups regarding plantar flexion angle — post-intervention

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Fig. 4
figure 4

Forest plot of comparison between study and control groups regarding plantar flexion angle — follow-up

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Fig. 5
figure 5

Forest plot of comparison between study and control groups regarding plantar flexors strength — post-intervention

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Fig. 6
figure 6

Forest plot of comparison between study and control groups regarding plantar flexors strength — follow-up

Full size image

Dorsiflexion angle

Two studies [39, 43] were included in a meta-analysis for dorsiflexion angle — post-intervention. As shown in Fig. 2, the total number of children included in the meta-analysis is 26 in study groups and 26 in control groups. The forest plot of mean difference across the two studies at 95% CI of mean difference is MD = 0.14 (95% CI of mean difference = −3.86, 4.13). Furthermore, the 95% confidence intervals of the overall effect estimate overlap the null effect value, so the meta-analysis level revealed a non-significant difference between the study groups and control groups (the overall effect P value is 0.95). The I2 statistic (I2 = 0%, P = 0.87, random-effects model) is expressed as a percentage and represents the total variability in the studies’ effect measure which is due to heterogeneity. The I2 value is ˂ 50%, and the test P value is ˃ 0.05 so the studies can be considered homogenous.

Plantar flexion angle

Two studies [41, 43] were included in a meta-analysis for plantar flexion angle — post-intervention. As shown in Fig. 3, the total number of children included in the meta-analysis is 44 in study groups and 44 in control groups. The forest plot of mean difference across the two studies at 95% CI of mean difference is MD = 0.32 (95% CI of mean difference = −0.10, 0.74). Furthermore, the 95% confidence intervals of the overall effect estimate overlap the null effect value, so the meta-analysis level revealed a non-significant difference between the study groups and control groups (the overall effect P value is 0.14). The I2 statistic (I2 = 0%, P = 0.79, random-effects model) is expressed as a percentage and represents the total variability in the studies’ effect measure which is due to heterogeneity. The I2 value is ˂ 50%, and the test P value is ˃ 0.05 so the studies can be considered homogenous.

Two studies [41, 43] were included in a meta-analysis for plantar flexion angle —follow-up. As shown in Fig. 4, the total number of children included in the meta-analysis is 44 in study groups and 44 in control groups. The forest plot of mean difference across the two studies at 95% CI of mean difference is MD = 0.24 (95% CI of mean difference = −0.32, 0.81). Furthermore, the 95% confidence intervals of the overall effect estimate overlap the null effect value, so the meta-analysis level revealed a non-significant difference between the study groups and control groups (the overall effect P value is 0.40). The I2 statistic (I2 = 44%, P = 0.18, random-effects model) is expressed as a percentage and represents the total variability in the studies’ effect measure which is due to heterogeneity. The I2 value is ˂ 50%, and the test P value is ˃ 0.05 so the studies can be considered homogenous.

Plantar flexors strength

Four studies [37, 41,42,43] were included in a meta-analysis for plantar flexors strength — post-intervention. As shown in Fig. 5, the total number of children included in the meta-analysis is 82 in the study groups and 71 in the control groups. The forest plot of mean difference across the four studies at 95% CI of mean difference is MD = 0.24 (95% CI of mean difference = −0.09, 0.56). Furthermore, the 95% confidence intervals of the overall effect estimate overlap the null effect value, so the meta-analysis level revealed a non-significant difference between the study groups and control groups (the overall effect P value is 0.15). The I2 statistic (I2 = 3%, P = 0.38, random-effects model) is expressed as a percentage and represents the total variability in the studies’ effect measure which is due to heterogeneity. The I2 value is ˂ 50%, and the test P value is ˃ 0.05 so the studies can be considered homogenous.

Four studies [37, 41,42,43] were included in a meta-analysis for plantar flexors strength — follow-up. As shown in Fig. 6, the total number of children included in the meta-analysis is 80 in the study groups and 70 in the control groups. The forest plot of mean difference across the four studies at 95% CI of mean difference is MD = 0.32 (95% CI of mean difference = 0.00, 0.65). Furthermore, the 95% confidence intervals of the overall effect estimate overlap the null effect value, so the meta-analysis level revealed a non-significant difference between the study groups and control groups (the overall effect P value is 0.05). The I2 statistic (I2 = 0%, P = 0.93, random-effects model) is expressed as a percentage and represents the total variability in the studies’ effect measure which is due to heterogeneity. The I2 value is ˂ 50%, and the test P value is ˃ 0.05 so the studies can be considered homogenous.

Discussion

Best practice in rehabilitation requires sufficient evidence before an intervention can be considered appropriate in a defined population. The current systematic review used systematic methods for searching for and appraises available studies in order to assess the quality and strength of evidence of different forms of exercises for equines in children with cerebral palsy. In this review, the outcomes included are dorsiflexion angle, plantar flexion angle, and plantar flexion strength. Strengthening exercises promote bone growth, lower blood sugar, aid in weight control, improve balance and posture, and alleviate joint stress and pain [44]. Stretching the calf muscles has been shown to improve ankle range of motion in both young and old patients [45]. Calf stretching exercises are commonly prescribed and the most common clinical approach for treating ankle joint equines. It promotes and maintains flexibility, reduces pathological pressures and forces, and enhances dynamic gait [46].

This review included randomized controlled trials. This design allows for the estimation of the effect of exercise training on equinus deformity in children with cerebral palsy. Randomization reduces selection bias and provides a comprehensive tool for examining cause–effect relationships between an intervention and an outcome, which makes the RCT the gold standard for intervention and impossible to achieve with any other study design [47].

All studies in this systematic review had random allocation of participants and similar baselines, reported results of between-group statistical comparisons, and provided measures of variability for at least one outcome. The eligibility criteria were specified in all studies. Five studies [37, 38, 40,41,42] had blinded assessors and concealed allocation. Only one study [42] had blinded participants and a blinded therapist. All the included studies obtained at least one outcome from more than 85% of the participants initially allocated, and five studies [37, 39,40,41,42] used an intention-to-treat analysis.

During normal gait, the coupling of ankle plantarflexion and knee extension moments during midstance promotes lower limb stability [48]. The soleus, an ankle plantarflexor muscle, restrains forward rotation of the tibia over the foot during stance and helps knee extension without the need for quadriceps activity [49, 50]. Equines are characterized by a reduction in ankle dorsiflexion range of motion and a limitation of the ankle joint complex in the sagittal plane associated with abnormal heel-to-toe loading during gait [49]. This limitation of ankle joint dorsiflexion is associated with impaired balance and functional ability [51, 52], as well as an increased risk of falling [53]. It also proposed that an equinus contributes to the development of gait pathologies by increasing the forefoot pressures, as the reduction in range of motion alters gait and forefoot loading patterns [51,52,53,54]. Increased stance phase knee extension in individuals with equinus is complicated by changes in the musculoskeletal system triggered directly or indirectly by the injury to the central nervous system. Knee hyperextension associated with equinus has been attributed to increased ankle plantar flexor stiffness from, for example, contractures [55], or changes in mechanical properties of sarcomeres secondary to the injury [56].

In this systematic review, strengthening exercises were used in five studies by Rayn et al. [37], Hosl et al. [39], Kruse et al. [43], Scholtes et al. [41], Dodd et al. [42]; combined stretching and strengthening exercises were used in a study by Kalkman et al. [38]; and eccentric stretching of the ankle joint was used in a study by Bohm et al. [40]. The duration of strengthening exercises ranged from 6 to 12 weeks. The strengthening exercises were performed three times per week, three to eight sets with eight to twelve repetitions.

The outcomes in the studies represent International Classification of Function (ICF) components of body structure and function [37,38,39,40,41,42,43] and activity and participation [37, 39,40,41,42].

Searle 2019 examined the effect of 8 weeks of stretching exercise of the calf muscle and found no significant impact, neither on the dorsiflexion angle nor on the plantar flexion pressure [57]. Continuous stretching can improve the range of motion [58]. Cui Zhang et al. found that resistance exercises for 16 weeks can improve ankle kinesthesia in the plantar flexion and dorsiflexion axis [59].

Ankle joint mobility, muscle strength, and walking performance can all be improved with exercise training that is suited to the subject’s condition [60]. As fatigue was increased in gastrocnemius medialis during walking among CP children [61] and that isometric plantar flexor strength explained at least 50% of the variance measures of walking capacity in adults with CP [62], as a result, resistance training, which improves muscle strength in the ankle plantar flexion muscles, may improve walking performance. Muscular strength, mechanical power, and speed can all be improved with strength and power training [63].

A study by Katsura et al. found that aquatic exercise reveals a significant effect of progressive resistance exercise on plantar flexors strength as a result of increasing triceps surae strength [64], the muscle which the main function is to flex the ankle and maintain the upright posture [65]. Kruse et al. [43] is the only study that shows a significant result in favour of progressive resistance exercise in the plantar flexors strength. They assumed that the absolute value differences were related to the normal growth against their hypothesis as there is no increase in gastrocnemius thickness. The resistance exercise may be nonspecific enough to modify the gastrocnemius architecture.

McHugh and Cosgrave have suggested that stretching before sports activities should be avoided because it decreases muscle strength [66]. This decrease in muscle strength is related to stretch duration [67] and caused by decreasing in muscle-tendon unit stiffness and neuromuscular activity [68, 69]. The length-tension relationship may be affected by potential mechanical changes in muscle-tendon unit stiffness [70]. Aerobic exercise improves muscle strength by increasing neuromuscular activity [71], improving the muscle length-tension relationship [72], accelerating metabolism of the muscle [73], and also psychological preparation [74]. As a result, combining stretching and aerobic exercise may improve the muscle strength deficit caused by stretching alone due to an increase in neuromuscular activity by decreasing MTU stiffness and increasing muscle strength [75].

The limitations of this review were the small number of studies included in the meta-analysis and the variable methodology of these studies (the type, duration, and intensity of exercise training) and the very small number of participants in two of the studies [39, 40]. Further research into the effect of various types of exercise should be carried out. The results of this systematic review need to be interpreted cautiously in the context of the small number of available high-quality studies as the effect of specific types of exercise on equinus deformity in children with CP has rarely been reported. Therefore, there is a need for further research with adequately powered studies and a large sample to provide adequate evidence of different exercise training on equines in children with cerebral palsy.

However, this systematic review recommends an urgent need for further and specified research on using different types of exercises not only in the management of equines in children with CP but also in the prevention of the deformity, using diverse outcome measures, including activities and participation. It is also recommended for further research for the combination of exercise training with other treatment methods for equinus in children with cerebral palsy.

Conclusions

This systematic review aims to fill the knowledge gap that exists between research and clinical practice in the use of exercise in the management of equinus deformity. It can provide the best intervention for equinus deformity in children with cerebral palsy. The current level of evidence to support the effectiveness of exercise on equinus deformity in children with cerebral palsy is still weak, so there is a clear need for more high-quality randomized controlled trials to establish strong evidence.

Availability of data and materials

All data generated or analysed during this study are included in the published article.

Abbreviations

AACPDM:

American Academy for Cerebral Palsy and Developmental Medicine

CI:

Confidence interval

CP:

Cerebral palsy

GMFCS:

Gross motor function classification system

PRISMA:

Preferred Reporting Items for Systematic Reviews and Meta-analysis

RCT:

Randomized controlled trial

GSC:

Gastrosoleus muscle complex

NS:

Non-significant

ICF:

International Classification of Function

MD:

Mean difference

PEDro:

Physiotherapy Evidence Database

Exp.gp:

Experimental group

con.gp:

Control group

yrs:

Years

m:

Month

References

  1. Munn Z, Porritt K, Lockwood C, Aromataris E, Pearson A. Establishing confidence in the output of qualitative research synthesis: the ConQual approach. BMC Med Res Methodol. 2014;14:108. https://doi.org/10.1186/1471-2288-14-108.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Pearson A, Jordan Z, Munn Z. Translational science and evidence-based healthcare: a clarification and reconceptualization of how knowledge is generated and used in healthcare. Nurs Res Pract. 2012;2012:792519. https://doi.org/10.1155/2012/792519.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Pearson A. Balancing the evidence: incorporating the synthesis of qualitative data into systematic reviews. JBI Rep. 2004;2:45–64. https://doi.org/10.1111/j.1479-6988.2004.00008.x.

    Article  Google Scholar 

  4. Steinberg E, Greenfield S, Mancher M, Wolman DM, Graham R. Clinical practice guidelines we can trust. Institute of Medicine. Washington, DC: National Academies Press; 2011. https://doi.org/10.17226/13058.

    Book  Google Scholar 

  5. Higgins J, Green S, eds. Cochrane handbook for systematic reviews of interventions. Version 5.1.0 (updated March 2011). ed: The Cochrane Collaboration 2011 https://handbook-5-1.cochrane.org.

  6. Rosenbaum P, Paneth N, Leviton A, et al. A report: the definition and classification of cerebral palsy April 2006. Dev Med Child Neurol Suppl. 2007;109:8–14. https://doi.org/10.1111/j.1469-8749.2007.tb12610.x.

    Article  PubMed  Google Scholar 

  7. Colver A, Fairhurst C, Pharoah PO. Cerebral palsy. Lancet. 2014;383(9924):1240–9. https://doi.org/10.1016/S0140-6736(13)61835-8.

    Article  PubMed  Google Scholar 

  8. Aisen ML, Kerkovich D, Mast J, et al. Cerebral palsy: clinical care and neurological rehabilitation. Lancet Neurol. 2011;10:844–52. https://doi.org/10.1016/s1474-4422(11)70176-4.

    Article  PubMed  Google Scholar 

  9. Domagalska M, Szopa A, Lembert D. A descriptive analysis of abnormal postural patterns in children with hemiplegic cerebral palsy. Med Sci Monit. 2011;17:110–6. https://doi.org/10.12659/msm.881396.

    Article  Google Scholar 

  10. Domagalska–Szopa M, Szopa A. Postural pattern recognition in children with unilateral cerebral palsy. Ther Clin Risk Manag. (2014) 10:113–120. https://doi.org/10.2147/TCRM.S58186.

  11. Kedem P, Scher DM. Foot deformities in children with cerebral palsy. Curr Opin Pediatr. 2015;27(1):67–74. https://doi.org/10.1097/mop.0000000000000180.

    Article  PubMed  Google Scholar 

  12. Shore BJ, Nathan White H, Graham K. Surgical correction of equinus deformity in children with cerebral palsy: a systematic review. J Child Orthop. 2010;4:277–90. https://doi.org/10.1007/2Fs11832-010-0268-4.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Aiona MD, Sussman MD. Treatment of spastic diplegia in patients with cerebral palsy: part II. J Pediatr Orthop B. 2004;13:S13–38. https://doi.org/10.1097/00009957-200405000-00016.

    Article  PubMed  Google Scholar 

  14. O’Connell PA, D’Souza L, Dudeney S, Stephens M. Foot deformities in children with cerebral palsy. J Pediatr Orthop. 1998;18:743–7 https://www.bibsonomy.org/bibtex/289369d9f08ac181416552c35d7a8712a/ar0berts.

    PubMed  Google Scholar 

  15. Gage JR. The identification and treatment of gait problems in cerebral palsy. London: Cambridge University Press; 2009. p. 327–43. https://doi.org/10.1097/BPO.0b013e3181d07f0c.

    Book  Google Scholar 

  16. Cottalorda J, Gautheron V, Metton G, Charmet E, Chavrier Y. Toe-walking in children younger than 6 years with cerebral palsy. The contribution of serial corrective casts. J Bone Jt Surg Br. 2000;82:541–4. https://doi.org/10.1302/0301-620X.82B4.0820541.

    Article  CAS  Google Scholar 

  17. Svehlik M, Zwick EB, Steinwender G, Kraus T, Linhart WE. Dynamic versus fxed equinus deformity in children with cerebral palsy: how does the triceps surae muscle work? Arch Phys Med Rehabil. 2010;91:1897–903. https://doi.org/10.1016/j.apmr.2010.09.005.

    Article  PubMed  Google Scholar 

  18. Cobeljic G, Bumbasirevic M, Lesic A, Bajin Z. The management of spastic equinus in cerebral palsy. Orthop Trauma. 2009;23:201–9. https://doi.org/10.1016/j.mporth.2009.05.003.

    Article  Google Scholar 

  19. Herzenberg JE, Lamm BM, Corwin C, et al. Isolated recession of the gastrocnemius muscle: the Baumann procedure. Foot Ankle Int. 2007;28(11):1154–9. https://doi.org/10.3113/2FFAI.2007.1154.

    Article  PubMed  Google Scholar 

  20. Damiano DL, Alter KE, Chambers H. New clinical and research trends in lower extremity management for ambulatory children with cerebral palsy. Phys Med Rehabil Clin North America. 2009;20(3):469–91. https://doi.org/10.1016/j.pmr.2009.04.005.

    Article  Google Scholar 

  21. Fowler, E.G., Kolobe, T.H., Damiano, D.L., Thorpe, D.E., Morgan, D.W., Brunstrom, J.E., Coster, W.J., Henderson, R.C., Pitetti, K.H., Rimmer, J.H., Rose, J., Stevenson, R.D., Section on Pediatrics Research Summit Participants and Section on Pediatrics Research Committee Task Force. Promotion of physical fitness and prevention of secondary conditions for children with cerebral palsy: section on pediatrics research summit proceedings. Physical Therapy. 2007. 8711:1495-1510. https://doi.org/10.2522/ptj.20060116

  22. Unger M, Faure M, Frieg A. Strength training in adolescent learners with cerebral palsy: a randomized controlled trial. Clinical Rehabilitation. 2006;20(6):469–77. https://doi.org/10.1191/0269215506cr961oa.

  23. Damiano DL, Kelly LE, Vaughn CL. Effects of quadriceps femoris muscle strengthening on crouch gait in children with spastic diplegia. Physical Therapy. 1995;75(8):658–67. https://doi.org/10.1093/ptj/75.8.658 discussion 668-71.

  24. Damiano DL, Abel MF. Functional outcomes of strength training in spastic cerebral palsy. Arch Phys Med Rehabil. 1998;79(2):119–25. https://doi.org/10.1016/S0003-9993%2898%2990287-8.

    Article  CAS  PubMed  Google Scholar 

  25. Wiart L, Darrah J, Kembhavi G. Stretching with children with cerebral palsy: what do we know and where are we going? Pediatr Phys Ther. 2008;20(2):173–8. https://doi.org/10.1097/pep.0b013e3181728a8c.

    Article  PubMed  Google Scholar 

  26. Novak I, Berry J. Home program intervention effectiveness evidence. Phys Occup Ther Pediatr. 2014;34(4):384–9. https://doi.org/10.3109/01942638.2014.964020.

    Article  PubMed  Google Scholar 

  27. Darrah J, Hickman R, O’Donnell M, Vogtle L, Wiart L. AACPDM methodology for developing systematic reviews of treatment interventions (revision 1.2). Milwaukee: American Academy for Cerebral Palsy and Developmental Medicine; 2008. https://doi.org/10.1097/2FPEP.0000000000000517.

    Book  Google Scholar 

  28. Wiart L, et al. Interrater reliability and convergent validity of the American Academy for cerebral palsy and developmental medicine methodology for conducting systematic reviews. DMCN. 2012;54:606–11. https://doi.org/10.1111/j.1469-8749.2012.04307.x.

    Article  Google Scholar 

  29. DeMorton N. The PEDro scale is a valid measure of the methodological quality of clinical trials: a demographic study. Aust J Physiother. 2009;55:129–33. https://doi.org/10.1016/s0004-9514(09)70043-1.

    Article  Google Scholar 

  30. Teasell R, Hsieh T, Aubut J, Eng J, Krassioukov A, Tu L. Venous thrombo embolism after spinal cord injury. Arch Phys Med Rehabil. 2009;90:232. https://doi.org/10.1016/j.apmr.2008.09.557.

    Article  PubMed  PubMed Central  Google Scholar 

  31. Sackett D, Strauss S, Richardson W, Rosenberg W, Haynes R. Evidence-based medicine: how to practice and teach EBM. Toronto: Churchill Livingstone; 2000. https://doi.org/10.1093/clinchem/47.9.1747.

    Book  Google Scholar 

  32. Cumpston M, Li T, Page MJ, Chandler J, Welch VA, Higgins JP, et al. Updated guidance for trusted systematic reviews: a new edition of the Cochrane Handbook for Systematic Reviews of Interventions. Cochrane Database Syst Rev. 2019;10(ED000142). https://doi.org/10.1002/14651858.ED000142.

  33. Aviva Petrie, Caroline Sabin. Medical Statistics at a Glance, 3rd ed., Blackwell Science Ltd., Oxford, USA, 2009, Ch 11, pp: 34. Medical Statistics at a Glance - Aviva Petrie, Caroline Sabin - كتب Google

  34. Janet L. Peacock, Phillip J. Peacock. Oxford handbook of medical statistics. Oxford Medical Publications, First published 2011, Ch 8, pp: 242. Oxford Handbook of Medical Statistics by Janet L. Peacock (goodreads.com)

  35. Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane handbook for systematic reviews of interventions version 6.2 (updated February 2021). Ch. 10. Cochrane, 2021. Available from www.training.cochrane.org/handbook

  36. Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372:n71. https://doi.org/10.1136/bmj.n71.

    Article  PubMed  PubMed Central  Google Scholar 

  37. Ryan JM, Lavelle G, Theis N, Noorkoiv M, Kilbride C, Korff T, et al. Progressive resistance training for adolescents with cerebral palsy: the STAR randomized controlled trial. Dev Med Child Neurol. 2020;62(11):1283–93. https://doi.org/10.1111/dmcn.14601.

    Article  PubMed  Google Scholar 

  38. Kalkman BM, Holmes G, Bar-On L, Maganaris CN, Barton GJ, Bass A, et al. Resistance training combined with stretching increases tendon stiffness and is more effective than stretching alone in children with cerebral palsy: a randomized controlled trial. Front Pediatr. 2019;7:333. https://doi.org/10.3389/fped.2019.00333.

    Article  PubMed  PubMed Central  Google Scholar 

  39. Hösl M, Böhm H, Eck J, Döderlein L, Arampatzis A. Effects of backward-downhill treadmill training versus manual static plantarflexor stretching on muscle-joint pathology and function in children with spastic Cerebral Palsy. Gait Posture. 2018;65:121–8. https://doi.org/10.1016/j.gaitpost.2018.07.171.

    Article  PubMed  Google Scholar 

  40. Böhm H, Rammelmayr MK, Döderlein L. Effects of climbing therapy on gait function in children and adolescents with cerebral palsy–a randomized, controlled crossover trial. Eur J Physiother. 2015;17(1):1–8. https://doi.org/10.3109/21679169.2014.955525.

    Article  Google Scholar 

  41. Scholtes VA, Becher JG, Janssen-Potten YJ, Dekkers H, Smallenbroek L, Dallmeijer AJ. Effectiveness of functional progressive resistance exercise training on walking ability in children with cerebral palsy: a randomized controlled trial. Res Dev Disabil. 2012;33(1):181–8. https://doi.org/10.1016/j.ridd.2011.08.026.

    Article  PubMed  Google Scholar 

  42. Dodd KJ, Taylor NF, Graham HK. A randomized clinical trial of strength training in young people with cerebral palsy. Dev Med Child Neurol. 2003;45(10):652–7. https://doi.org/10.1017/S0012162203001221.

    Article  PubMed  Google Scholar 

  43. Kruse A, Schranz C, Svehlik M, Tilp M. The effect of functional home-based strength training programs on the mechano-morphological properties of the plantar flexor muscle-tendon unit in children with spastic cerebral palsy. Pediatr Exerc Sci. 2019;31(1):67–76. https://doi.org/10.1123/pes.2018-0106.

    Article  PubMed  Google Scholar 

  44. Jürgens A, Witt T, Gottsberger G. Pollen grain numbers, ovule numbers and pollen-ovule ratios in Caryophylloideae: correlation with breeding system, pollination, life form, style number, and sexual system. Sex Plant Reprod. 2002;14(5):279–89. https://doi.org/10.1007/s00497-001-0124-2.

    Article  Google Scholar 

  45. Radford J, Burns J, Buchbinder R, Landorf K, Cook C. Does stretching increase ankle dorsiflexion range of motion? A systematic review. Br J Sports Med. 2006;40(10):870–5. https://doi.org/10.1136/bjsm.2006.029348.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  46. Valmassy RL. Clinical biomechanics of the lower extremities. Missouri: Mosby Year Book Inc.; 1996. (PDF) Clinical Biomechanics Of The Lower Extremities Download eBOOK (bookarchive.net)

    Google Scholar 

  47. Hariton E, Locascio JJ. Randomised controlled trials - the gold standard for effectiveness research: study design: randomised controlled trials. BJOG. 2018;125(13):1716. https://doi.org/10.1111/1471-0528.15199.

    Article  PubMed  PubMed Central  Google Scholar 

  48. Gage JR, Novacheck TF. An update on the treatment of gait problems in cerebral palsy. J Pediatr Orthop B. 2001;10:265–74. https://doi.org/10.1097/00009957-200110000-00001.

    Article  CAS  PubMed  Google Scholar 

  49. Perry J. Gait analysis: normal and pathological function. Thorofare: Slack Inc; 1992. Gait Analysis: Normal and Pathological Function - Jacquelin Perry - Google Books

    Google Scholar 

  50. Neptune RR, Kautz SA, Zajac FE. Contributions of the individual ankle plantar flexors to support, forward progression and swing initiation during walking. J Biomech. 2001;34:1387–98. https://doi.org/10.1016/s0021-9290(01)00105-1.

    Article  CAS  PubMed  Google Scholar 

  51. Menz HB, Morris ME, Lord SR. Foot and ankle characteristics associated with impaired balance and functional ability in older people. J Gerontol Ser A Biol Med Sci. 2005;60:1546–52. https://doi.org/10.1093/gerona/60.12.1546.

    Article  Google Scholar 

  52. Spink MJ, Fotoohabadi MR, Wee E, Hill KD, Lord SR, Menz HB. Foot and ankle strength, range of motion, posture, and deformity are associated with balance and functional ability in older adults. Arch Phys Med Rehabil. 2011a;92:68–75. https://doi.org/10.1016/j.apmr.2010.09.024.

    Article  PubMed  Google Scholar 

  53. Menz HB, Morris ME, Lord SR. Foot and ankle risk factors for falls in older people: a prospective study. J Gerontol A Biol Sci Med Sci. 2006;61:866–70. https://doi.org/10.1093/gerona/61.8.866.

    Article  PubMed  Google Scholar 

  54. Bowers AL, Castro MD. The mechanics behind the image: foot and ankle pathology associated with gastrocnemius contracture. Semin Musculoskeltal Radiol. 2007;11:83–90. https://doi.org/10.1055/s-2007-984418.

    Article  Google Scholar 

  55. Maurer BT, Siegler S, Hillstrom HJ, Selby-Silverstein L, Farrett WD, Downey MS. Quantitative identification of ankle equinus with applications for treatment assessment. Gait and Posture. 1995;3(1):19–28. https://doi.org/10.1016/0966-6362(95)90805-3.

    Article  Google Scholar 

  56. Friden J, Lieber RL. Spastic muscle cells are shorter and stiffer than normal cells. Muscle Nerve. 2003;26:157–64. https://doi.org/10.1002/mus.10247.

    Article  Google Scholar 

  57. Searle A, Spink MJ, Oldmeadow C, Chiu S, Chuter VH. Calf muscle stretching is ineffective in increasing ankle range of motion or reducing plantar pressures in people with diabetes and ankle equinus: a randomised controlled trial. Clin Biomech. 2019;69:52–7. https://doi.org/10.1016/j.clinbiomech.2019.07.005.

    Article  Google Scholar 

  58. Trajano GS, Nosaka K, Seitz LB, Blazevich AJ. Intermittent stretch reduces force and central drive more than continuous stretch. Med Sci Sport Exerc. 2014;46(5):902–10. https://doi.org/10.1249/mss.0000000000000185.

    Article  Google Scholar 

  59. Zhang C, Sun W, Yu B, Song Q, Mao D. Effects of exercise on ankle proprioception in adult women during 16 weeks of training and eight weeks of detraining. Res Sports Med. 2015;23(1):102–13. https://doi.org/10.1080/15438627.2014.915835.

    Article  PubMed  Google Scholar 

  60. Francia P, Anichini R, De Bellis A, Seghieri G, Lazzeri R, Paternostro F, et al. Diabetic foot prevention: the role of exercise therapy in the treatment of limited joint mobility, muscle weakness and reduced gait speed. Italian journal of anatomy and embryology. 2015;120(1):21. https://doi.org/10.13128/IJAE-16470.

    Article  PubMed  Google Scholar 

  61. Eken MM, Braendvik SM, Bardal EM, Houdijk H, Dallmeijer AJ, Roeleveld K. Lower limb muscle fatigue during walking in children with cerebral palsy. Dev Med Child Neurol. 2019;61:212–8. https://doi.org/10.1111/dmcn.14002.

    Article  PubMed  Google Scholar 

  62. Gillett JG, Lichtwark GA, Boyd RN, Barber LA. Functional capacity in adults with cerebral palsy: lower limb muscle strength matters. Arch Phys Med Rehabil. 2018;99:900–6. https://doi.org/10.1016/j.apmr.2018.01.020.

    Article  PubMed  Google Scholar 

  63. Lum D, Barbosa TM. Brief review: effects of isometric strength training on strength and dynamic performance. Int J Sports Med. 2019;40(06):363–75. https://doi.org/10.1055/a-0863-4539.

    Article  PubMed  Google Scholar 

  64. Katsura Y, Yoshikawa T, Ueda SY, Usui T, Sotobayashi D, Nakao H, et al. Effects of aquatic exercise training using water-resistance equipment in elderly. Eur J Appl Physiol. 2010;108(5):957–64. https://doi.org/10.1007/s00421-009-1306-0.

    Article  PubMed  Google Scholar 

  65. Tokuno CD, Carpenter MG, Thorstensson A, Garland SJ, Cresswell AG. Control of the triceps surae during the postural sway of quite standing. Acta Physiol. 2007;1. https://doi.org/10.1111/j.1748-1716.2007.01727.x.

  66. McHugh MP, Cosgrave CH. To stretch or not to stretch: the role of stretching in injury prevention and performance. Scand J Med Sci Sports. 2010;20(2):169–81. https://doi.org/10.1111/j.1600-0838.2009.01058.x.

    Article  CAS  PubMed  Google Scholar 

  67. Simic L, Sarabon N, Markovic G. Does pre-exercise static stretching inhibit maximal muscular performance? A meta-analytical review. Scand J Med Sci Sports. 2013;23(2):131–48. https://doi.org/10.1111/j.1600-0838.2012.01444.x.

    Article  CAS  PubMed  Google Scholar 

  68. Mizuno T, Matsumoto M, Umemura Y. Decrements in stiffness are restored within 10 min. Int J Sports Med. 2013;34(6):484–90. https://doi.org/10.1055/s-0032-1327655.

    Article  CAS  PubMed  Google Scholar 

  69. Mizuno T, Matsumoto M, Umemura Y. Stretching-induced deficit of maximal isometric torque is restored within 10 minutes. J Strength Cond Res. 2014;28(1):147–53. https://doi.org/10.1519/jsc.0b013e3182964220.

    Article  PubMed  Google Scholar 

  70. Fowles JR, Sale DG, MacDougall JD. Reduced strength after passive stretch of the human plantarflexors. J Appl Physiol. 2000;89(3):1179–88. https://doi.org/10.1152/jappl.2000.89.3.1179.

    Article  CAS  PubMed  Google Scholar 

  71. Stewart D, Macaluso A, De Vito G. The effect of an active warm-up on surface EMG and muscle performance in healthy humans. Eur J Appl Physiol. 2003;89(6):509–13. https://doi.org/10.1007/s00421-003-0798-2.

    Article  PubMed  Google Scholar 

  72. Bishop D. Warm up I: potential mechanisms and the effects of passive warm up on exercise performance. Sports Med. 2003;33(6):439–54. https://doi.org/10.2165/00007256-200333060-00005.

    Article  PubMed  Google Scholar 

  73. Bishop D, Bonetti D, Dawson B. The influence of pacing strategy on VO2 and supramaximal kayak performance. Med Sci Sports Exerc. 2002;34(6):1041–7. https://doi.org/10.1097/00005768-200206000-00022.

    Article  PubMed  Google Scholar 

  74. O’Sullivan K, Murray E, Sainsbury D. The effect of warm-up, static stretching and dynamic stretching on hamstring flexibility in previously injured subjects. BMC Musculoskelet Disord. 2009;10:37. https://doi.org/10.1186/1471-2474-10-37.

    Article  PubMed  PubMed Central  Google Scholar 

  75. Takeuchi K, Nakamura M, Tsukuda F, Miyakawa S. The effects of using a combination of static stretching and aerobic exercise on muscle tendon unit stiffness and strength in ankle plantar-flexor muscles. Eur J Sport Sci. 2020;22(2):297–303. https://doi.org/10.1080/17461391.2020.1866079.

    Article  Google Scholar 

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  1. Department of Physical Therapy for Paediatrics, Faculty of Physical Therapy, Cairo University, Giza, Egypt

    Dina Abd Elwahab Zahran, Walaa Mahfouz Bahr & Faten Hassan Abd Elazim

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DA and WM performed an electronic search and data extraction independently and assessed the methodological quality of included studies where discrepancies between them were resolved by consultation with the third author FA to reach the final decision. The authors read and approved the final manuscript.

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Zahran, D.A.E., Bahr, W.M. & Abd Elazim, F.H. Systematic review: exercise training for equinus deformity in children with cerebral palsy. Bull Fac Phys Ther 27, 37 (2022). https://doi.org/10.1186/s43161-022-00093-9

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Keywords

  • Cerebral palsy
  • Exercise
  • Treatment
  • Foot deformity
  • Equines
  • Systematic review
  • Children